Learn the basics
Chemsex fundamentals
What chemsex is, the risks, staying safer, and how to talk about it. Every fact is referenced.
Contents
Part 1 The fundamentals The fundamentals
What chemsex is, who it affects, why people do it, the drugs and the words people use.
In this part
Part 2 The risks The risks
What can go wrong, and what to look out for.
In this part
Part 3 G overdose and harm reduction G overdose and harm reduction
A short summary. Our Staying safer page has the full detail.
Part 4 Talking and referring Talking and referring
How to start the conversation, and where to find out more.
In this part
References
- ONS (2025) Drug misuse in England and Wales: year ending March 2025.
- Home Office (2014) Drug misuse: findings from the 2013/14 Crime Survey for England and Wales, chapter 5.
- Dawson & George (2023) Mapping report for Public Health Wales, Swansea University.
- Frankis J, Flowers P, McDaid L, Bourne A (2018) Low levels of chemsex amongst men who have sex with men… Sexual Health.
- Blomquist PB et al. (2020) Characteristics and sexual health service use of MSM engaging in chemsex. Sex Transm Infect 96:590-595.
- The EMIS Network (2019) EMIS-2017: The European MSM Internet Survey. ECDC.
- Glynn RW et al. (2018) Chemsex, risk behaviours and STIs among MSM in Dublin. Int J Drug Policy 52:9-15.
- Bourne A et al. (2014) The Chemsex Study. Sigma Research, LSHTM.
- Brook G et al. (2019) BASHH UK national guideline for consultations requiring sexual history taking.
- European Union Drugs Agency (EUDA) FAQ: gender and drugs in Europe.
- Harm Reduction International (2021) Chemsex briefing.
- Public Health Wales, Chemsex.
- FRANK drug pages: GHB/GBL, cocaine, ketamine, poppers, cannabis.
- With You (2024) Chemsex: how to reduce harm.
- NHS Hampshire and Isle of Wight sexual health: chemsex support.
- Drinkaware, Alcohol and illegal drugs (cocaethylene).
- NHS: Priapism; Erectile dysfunction; Sildenafil.
- MHRA (13 Feb 2026) 20 million illegal erectile dysfunction pills seized.
- ONS (17 Oct 2025) Deaths related to drug poisoning in England and Wales: 2024 registrations.
- UKHSA (2026) Sexually transmitted Shigella spp. in England: 2016 to 2025.
- NHS: Hepatitis A; Hepatitis C; C. difficile; Sepsis; Flu.
- UKHSA: People who inject drugs: infection risks, guidance and data.
- BASHH (2025) UK national guideline for doxycycline post-exposure prophylaxis (DoxyPEP).
- Public Health Wales: Hepatitis B vaccine; Mpox vaccine.
- WEDINOS drug testing; Barod needle exchange.
- Helplines: DAN 24/7, Samaritans, Galop.
- GMMH NHS FT, Overdose advice.
- Terrence Higgins Trust, What to do in a GHB emergency.
- Crew (Scotland), How to respond to a drug overdose.
- FRANK, What to do in an emergency.
- Resuscitation Council UK (2025) Adult basic life support guidelines.
- London Friend, Mephedrone.
- Gay Men’s Health Collective (GMHC) Safer 2 pack: ‘Using G’ booklet. Conference material, London Chemsex Conference 2026.
- London Chemsex Conference 2026 (14 Oct 2026, GMHC and Antidote): session slides.
- Baldry G et al. (2026) Chemsex-associated drug use… UK online community survey, 2024 (UKHSA RiiSH). Int J STD & AIDS.
- Pollard A, Nadarzynski T, Llewellyn C (2018) Syndemics of stigma, minority-stress… Culture, Health & Sexuality 20(4).
- Rewbury R et al. (2017) Poppers maculopathy case series. Br J Ophthalmol 101(11).
- Meyer IH (2003) Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations. Psychological Bulletin.
- Viagra 100 mg: Summary of Product Characteristics. Electronic medicines compendium.
- Van Cauter E et al. (1997) GHB, slow-wave sleep and growth hormone. J Clin Invest 100(3).
- Chin MY, Kreutzer RA, Dyer JE (1992) Acute poisoning from GHB in California. West J Med 156(4).
- UKHSA (26 Mar 2026) What is Shigella?
- NHS: Gonorrhoea (sharing sex toys).
- Randolph et al. (2026) Cutaneous manifestations of injection drug use. JAAD Reviews 7.
- Sheffield Hallam University for GEO and DLUHC (2024) LGBT people’s experiences of homelessness.
- Antidote (London Friend) presentation, London Chemsex Conference 2026, as reported by Day One Club.
- St John Ambulance Cymru: free First Aid Awareness eLearning.
- British Red Cross: free First aid app.
- Home Office (2026) Crime and Policing Act 2026 factsheet: cuckooing.
- Misuse of Drugs Act 1971 (Amendment) Order 2022: GHB, GBL reclassified to Class B.
- GOV.UK, Drugs penalties.
- ACMD (28 Jan 2026) Ketamine: an updated review of use and harms.
- ACMD, Alkyl nitrites; Psychoactive Substances Act 2016, Schedule 1.
- Gay Men’s Health Collective, London Chemsex Conference 2026: frontline experience as presented, not published data.
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